New Jersey, USA: A new study has found that popular therapies such as inhalers are often ineffective in severe asthma attacks.
Inhalers (corticosteroids) are used as an emergency treatment during an asthma attack to reduce the swelling and irritation of the airways. It is effective in mild asthma, but it is often ineffective in people with severe asthma.
Reynold Penny Terry Jr., co-author of the study and vice chancellor of clinical and translational sciences at Rutgers University in New Jersey, said the study looked at the reasons why conventional therapies are ineffective for people with severe asthma.
Reynolds and his colleagues found that two naturally occurring factors (which stimulate cell division) activate the respiratory tract of patients with severe asthma when patients use inhalers and Inhibits the activity of the drug. These two factors are fibroblastic growth factor (FGF) and granulocytic colony forming growth factor.
“If we find new ways to treat severe asthma that could directly affect the above factors, we may be able to restore steroid sensitivity and improve outcomes,” Reynolds said.